This is from the UCSD Medical Images site.
DRESS Syndrome - Drug Reaction with Eosinophilia and Systemic Symptoms. Also known as drug hypersensitivity reactions.
These commonly present 2 or more weeks after initiating a new medication, and is manifested by:
- Fever
- Rash: papular, macular, bullous
- Lymphadenopathy
- Arthralgias
- Hepatitis
- Eosinophilia (in many cases)
Medications commonly associated with DRESS syndrome include "aromatic" anticonvulsants (phenytoin, carbamazepine, and phenobarbitol) - but can occur with other anticonvulsants as well. Other classic drugs include NSAIDS, abacavir, and allopurinol. Treatment revolves around stopping the culpret agent, supportive care, and perhaps steroid therapy in severe cases.
In the case of abacavir, a drug used in HIV treatment, hypersensitivity reactions are known to occur in those who are HLA B5701-positive. Screening programs are now widely used to prevent this reaction. Here is the sentinel article from NEJM. You will be hearing a lot more about "personalized medicine" in the near future.
ReplyDeleteMy husband was diagnosed with early onset Parkinson's disease at 57.his symptoms were shuffling of feet,slurred speech, low volume speech, degradation of hand writing, horrible driving skills, right arm held at 45 degree angle, things were tough for me, but now he finally free from the disease with the help of total cure ultimate health home, he now walks properly and all symptoms has reversed, he had trouble with balance especially at night, getting into the shower and exiting it is difficult,getting into bed is also another thing he finds impossible.we had to find a better solution for his condition which has really helped him a lot,the biggest helped we had was ultimatehealthhome they walked us through the proper steps,am highly recommended this ultimatehealthhome@gmail.com to anyone who needs help.
I really want to thank Dr Emu for saving my marriage. My wife really treated me badly and left home for almost 3 month this got me sick and confused. Then I told my friend about how my wife has changed towards me. Then she told me to contact Dr Emu that he will help me bring back my wife and change her back to a good woman. I never believed in all this but I gave it a try. Dr Emu casted a spell of return of love on her, and my wife came back home for forgiveness and today we are happy again. If you are going through any relationship stress or you want back your Ex or Divorce husband you can contact his whatsapp +2347012841542 or email emutemple@gmail.com website: Https://emutemple.wordpress.com/
DeleteI was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
ReplyDeleteliver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.